Plan your trip to the Hotel Republic San Diego, Autograph Collection for a distinctive blend of modern convenience and boutique sophistication. Our luxury hotel, which places you in the heart of downtown San Diego, near the Gaslamp Quarter and Little Italy, features a remarkable variety of helpful resources to ensure an unforgettable hotel stay in San Diego. Unwind after a busy day in downtown San Diego in your spacious, contemporary hotel room or suite; each hotel room is furnished with an assortment of luxury amenities. In addition, we offer exquisite on-site dining at Trade, our hotel restaurant, a well-equipped gym, and a business center. Boasting versatile, thoughtfully appointed space and state-of-the-art planning and catering services, our hotel is one of downtown San Diego's top event destinations, while our prime placement allows for easy access to Petco Park and the San Diego Convention Center. Lend yourself to modern luxury at the Hotel Republic San Diego, Autograph Collection.